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Microsoft's MAI-DxO diagnoses hard cases far better than generalist physicians in a peer-reviewed Science study

AspireAI · Science (Microsoft AI)
Microsoft gave its diagnostic AI the same job as a doctor: start with a chief complaint, then decide what to ask and which test to order next. In a peer-reviewed Science study, that setup, called MAI-DxO, reached 83.2% accuracy on 304 complex New England Journal of Medicine cases, versus 36.1% for generalist physicians with reference materials. On 325 emergency-department cases, it scored 80.3% versus 46.8%. It works like a junior doctor doing a workup: every answer changes the next test, and the system weighs cost along the way. The honest limit: this was a controlled, text-only benchmark. It did not compare against specialist teams, use imaging or pathology slides, or measure real patient outcomes. https://www.science.org/doi/10.1126/science.aeh7930
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