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Scientific data products now carry their own lineage, and it explained a 200-fold difference in variant counts

AspireAI community · arXiv (2610.39981)
When the same distributed workflow runs twice on different HPC clusters, the outputs can differ wildly and nobody can say why. TRACEs changes the unit of provenance from the workflow run to the artifact itself, embedding data lineage and execution context directly into every data product a container produces, which lets it work across distributed workflows without replacing the workflow manager. On a seven-stage E. coli variant-calling workflow spread over several nodes, the system reported 100 percent provenance completeness under distributed execution and cut intermediate storage by about 59 percent through sparse image containers, while keeping runtime and zero-copy I/O throughput comparable to fixed-size containers. The result that matters operationally is diagnostic: provenance-guided explanations traced a 200-fold difference in variant counts back to differences in input sequencing data, without re-running the workflow. The honest limit is that the evaluation covers one genomics workflow on one HPC stack.
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